A protein has been found to slow the effects of ageing in mice, and human trials are now underway, with experts suggesting it could improve various aspects of health, including sleep, fertility, heart protection, and brain function, potentially extending lifespan. The supplement, spermidine, is already available in the UK, with some doctors prescribing it for conditions ranging from heart disease and diabetes to cancer. This natural protein supports cell reproduction and is present in cells throughout the body. While the body produces a significant amount of spermidine internally, the remainder is obtained from the diet.
As individuals age, the natural production of spermidine decreases, and scientists believe that increasing intake could offer significant health benefits. Foods rich in spermidine, such as wheatgerm, shitake mushrooms, green peppers, broccoli, and mature cheese, have been linked to improved heart health and longevity. Intermittent fasting diets have also been found to elevate spermidine levels in humans.
Dr Olivia Lesslar, an Australian longevity specialist, has reported prescribing spermidine to patients with various health conditions, such as kidney disease, diabetes, and cancer, noting improvements in energy levels and even aesthetic benefits like thicker hair and stronger nails. The European Food Safety Agency recommends up to 6mg of spermidine supplements daily as safe for humans. Apart from occurring naturally in the body and certain foods, spermidine supplements can be purchased online for as little as 25p per pill.
These findings highlight the potential of spermidine to positively impact health and ageing-related concerns, offering a new avenue for supporting overall well-being.